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What Causes
Kidney Disease?

The two main culprits behind kidney disease are diabetes and high blood pressure, which account for two-thirds of all CKD cases.

    Other conditions that affect the kidneys are:

    • Glomerulonephritis, a group of diseases that cause inflammation and damage to the kidney's filtering units. These disorders are the third most common type of kidney disease.
    • Inherited diseases, such as polycystic kidney disease, which causes large cysts to form in the kidneys and damage the surrounding tissue.
    • Malformations that occur as a baby develops in its mother's womb. For example, a narrowing may occur that prevents normal outflow of urine and causes urine to flow back up to the kidney. This causes infections and may damage the kidneys.
    • Lupus and other diseases that affect the body's immune system.
    • Obstructions caused by problems like kidney stones, tumors or an enlarged prostate gland in men.
    • Repeated urinary infections.